Fig. 2
From: Role of circulating molecules in age-related cardiovascular and metabolic disorders

Circulating molecules characterized to suppress (inhibitory arrow) or enhance (arrow) described conditions. The question mark indicates inconsistent or controversial findings among papers. Undercarboxylated osteocalcin (ucOC), mesencephalic astrocyte-derived neurotrophic factor (MANF), growth differentiation factor (GDF), insulin-like growth factor-1 (IGF-1), osteocalcin (OC), growth hormone (GH), fibroblast growth factor 21 (FGF-21), tumor necrosis factor α (TNF-α), angiotensin II (Ang-II)