Fig. 3
From: Arthritis-associated osteoclastogenic macrophage, AtoM, as a key player in pathological bone erosion

Observation of osteoclasts in the interface between the inflamed synovium and bone surface. Osteoclasts were observed using an inverted two-photon microscopy. This is a representative result. Blue, second-harmonic generation (SHG); Red, TRAP-tdTomato; Arrow heads, representative bone resorption bits; Scale bar: 30 μm