Fig. 8
From: A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis
Safety of Alb-CTLA4Ig. Splenocytes from PBS-, mCTLA4Ig-, or mAlb-CTLA4Ig-treated CIA mice were stimulated with 25 μg/ml M. tuberculosis extracts for 72 h. Proliferation (BrdU incorporation) of CD45+ splenocytes (A), CD3+ T cells (B), and B220+ B cells (C) was analyzed by flow cytometry. Representative data from two independent experiments are shown