Fig. 1

HFs de novo regeneration in mice. A Experimental steps. B Representative pictures of HFs de novo regeneration after wounding. C 3W mice regenerated more HFs than 7W mice (7W vs 3W, 1.5 ± 0.82 vs 130.5 ± 29.51, n = 10). D Representative photos of Lgr5 HFSCs regeneration in 3W Lgr5 + /mTmG mice. Yellow arrows point to regenerated Lgr5 HFSCs. The yellow dashed line represents the wound margin. ***P < 0.005