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Fig. 3 | Inflammation and Regeneration

Fig. 3

From: Lactobacillus reuteri NCHBL-005 improves wound healing by promoting the activation of fibroblasts through TLR2/MAPK signaling

Fig. 3

Suppression of L. reuteri NCHBL-005-induced fibroblast proliferation and differentiation through MAPK inhibition. A Proliferation of L929 fibroblasts treated with MAPK inhibitors and L. reuteri NCHBL-005 at 24, 48, and 72 h post-treatment (mean ± SD). B Immunofluorescence staining of α-SMA (green) and DAPI (blue) in L929 fibroblasts. The significance of differences among the groups was assessed using two-way ANOVA, with the level of significance set at *p < 0.05. Ctrl. Control; LR, L. reuteri NCHBL-005; SB, SB203580; SP, SP600125; PD, PD0325901; α-SMA, α-smooth muscle actin; DAPI, 4′,6-diamidino-2-phenylindole; ANOVA, analysis of variance; SD, standard deviation

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Inflammation and Regeneration

ISSN: 1880-8190

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